March 2026
I Fixed My Sleep, Iron, Vitamin D, Caffeine, Alcohol, and Air Quality. I Was Still Foggy. It Was My Cat.
I spent over a year systematically testing every intervention I could find for brain fog. One at a time. With a baseline between each. CO2 monitor in the bedroom. Morning electrolytes. Ferritin optimization. Vitamin D loading. Magnesium. Caffeine elimination. Alcohol elimination. Daily exercise.
Each one helped. Each one peeled off a layer. My cognitive function improved significantly. Morning grogginess gone. Afternoon crashes gone. Working memory better. Verbal fluency better.
But I wasn't clear. Maybe 60 to 70% better. A massive improvement but not what I remembered my brain being capable of. There was still this film over my thinking that wouldn't lift no matter what I optimized. And a few symptoms that none of the fundamentals touched at all.
The rage. That never made sense. I'm not an angry person. Never have been. But for months I'd been snapping at people over nothing. Disproportionate explosive reactions that didn't fit my personality followed by this confused feeling of what just happened. Fixing my ferritin didn't touch it. Fixing my sleep didn't touch it. Exercise helped my mood overall but the sudden rage episodes kept coming through.
The insomnia. Not the tired kind. The wired at 2am kind. Brain running full speed producing nothing. Heart rate up for no reason. Magnesium helped my sleep quality but this was different. I'd fall asleep fine then wake at 1 or 2am completely wired. That pattern didn't match any of the sleep interventions I'd tried.
And foot pain. This persistent ache in my feet that started around the same time as everything else. Went to a doctor. Plantar fasciitis. Stretches and orthotics. Didn't help. Didn't connect it to the fog at the time because why would foot pain be related to brain fog.
I kept researching because the remaining 30% was driving me crazy. I'd fixed everything the biohacking world tells you to fix. I had the blood work to prove the nutrients were optimized. I was sleeping well, exercising daily, no caffeine, no alcohol, good air quality. And I was still foggy with unexplained rage and insomnia and foot pain that nobody could explain.
Then I found the work of Edward Breitschwerdt at NC State.
His lab has been publishing on a bacteria called Bartonella henselae for over a decade. It lives in about 40% of cats at some point in their lives. Gets under their claws from flea feces. You get scratched. Bacteria enters your blood. Most doctors know this as cat scratch fever. Mild. Self-limiting. Few weeks and done.
What they don't know is that in some people it doesn't clear. Bartonella is an intracellular pathogen. It gets inside your red blood cells and the endothelial cells lining your blood vessels including the ones in your brain. Hides inside your own cells. Your immune system can't see it properly. It sits there causing chronic neuroinflammation for months or years.
His 2019 paper documented a boy who developed seizures and psychiatric symptoms from confirmed Bartonella in his blood. Treated with antibiotics. Resolved. His 2024 review called Neurobartonelloses: emerging from obscurity catalogued the full spectrum. Encephalitis. Neuropathy. Cerebral vasculitis. Psychiatric symptoms including psychosis. A 2024 Frontiers in Psychiatry study found Bartonella DNA more prevalent in patients with psychosis than healthy controls. In February 2025 he published a family case study. Whole household infected through shared pets. All with neuropsychiatric symptoms.
I read all of this and then I thought backwards.
The symptoms that the fundamentals didn't fix. The rage. The wired insomnia. The foot pain. The residual fog. When did all of that actually start.
I'd gotten a kitten. A rescue. She had fleas when we got her. Treated them fast but she scratched me a few times before that. I didn't think about it once at the time. Cat scratches are normal.
I went to my GP and asked for Bartonella testing. She ran the standard IFA antibody test. Negative. She said see, not Bartonella.
But I'd read enough of Breitschwerdt's work to know the standard test misses chronic infections. The bacteria is intracellular. Your immune system may never mount a detectable antibody response. A negative IFA doesn't rule out Bartonella. It rules out a detectable antibody response. Those aren't the same thing.
I pushed for enrichment PCR. Had to show her the papers. She'd never heard of it. Eventually got tested properly.
Positive.
Treatment was months of antibiotics. Not weeks. I'm not going to name specific drugs because chronic Bartonella needs to be managed by someone who knows the protocols.
First few weeks were rough. Felt worse before better. Then the insomnia broke. First time in months I slept through to my alarm without the 2am wired awakening. Then the rage started fading. My partner noticed before I did. She said you haven't snapped at me in weeks.
The last of the fog lifted over months 3 and 4. Not a switch. More like the remaining film over my thinking slowly dissolved. The foot pain improved last. Not fully gone but maybe 80% better.
Here's the thing that gets me. I'd done everything right with the fundamentals. And they worked. The CO2 fix worked. The electrolytes worked. The ferritin worked. The vitamin D worked. The magnesium worked. Quitting caffeine worked. Quitting alcohol worked. Exercise worked. Each one peeled off a layer of fog.
But underneath all of those layers was an infection that none of that could touch. And if I'd stopped at 70% better and accepted that as my new normal I'd still be living with rage attacks and wired insomnia and foot pain and a thin film of fog over everything. Because no amount of electrolytes fixes a bacterial infection hiding inside your blood vessel walls.
The symptom pattern I now flag every time I see it
Brain fog that started suddenly. You can roughly point to when it began.
Rage that doesn't fit your personality. The kind that scares you afterwards.
Anxiety or panic that SSRIs don't touch.
Insomnia. The wired kind not the tired kind.
Foot pain nobody can explain.
Shin streaks. Linear slightly raised marks on shins or thighs that don't look like stretch marks. Look at your legs right now.
Any one of these alone means nothing. Four or more with a history of cat or flea exposure and I'd look at Bartonella before I'd look at anything else.
If this fits you
Don't accept a negative IFA as the final answer. Ask specifically for enrichment PCR or digital droplet PCR. You'll probably have to show your doctor the research. This isn't fringe. Breitschwerdt has over a decade of peer reviewed publications in Frontiers, Pathogens, and the Journal of Central Nervous System Disease.
What about the cat
I'm not a vet. But here's what I learned when I went down this road.
Most cats that carry Bartonella show no symptoms at all. Your cat isn't sick. It's a carrier. You won't know by looking at it.
Kittens are higher risk than adult cats. They carry higher bacterial loads and they scratch more. Rescue kittens with fleas are the highest risk combination. That was my situation exactly.
Cats can be tested. A vet can run PCR on blood to check for Bartonella. But a negative doesn't mean they never had it. Cats can clear the bacteria on their own over time. A cat that infected you 6 months ago might test clean today.
The single most important thing you can do is flea control. Bartonella lives in flea feces. Fleas defecate on the cat. Feces gets under the claws. Cat scratches you. That's the transmission chain. Break it at the flea step and the rest doesn't happen. Topical or oral flea preventative. Year round. Not just summer.
Beyond that. Keep claws trimmed. Don't let cats lick open wounds. If you get scratched wash it immediately and thoroughly. Don't play rough with kittens using your hands.
Don't get rid of your cat. That isn't the message here. The message is keep the cat flea-free, handle scratches properly, and if you develop unexplained neuropsychiatric symptoms with the timeline and pattern I described, tell your doctor you have cat exposure.
And if you've already optimized the fundamentals and there's still a piece that won't budge, consider the possibility that something is hiding underneath all of it. Sometimes the last 30% is the thing nobody thought to test for.
References
- Breitschwerdt EB, Greenberg R, Maggi RG, Mozayeni BR, Lewis A, Bradley JM. Bartonella henselae bloodstream infection in a boy with pediatric acute-onset neuropsychiatric syndrome. J Central Nervous System Disease. 2019. DOI: 10.1177/1179573519832014
- Bush JC, Robveille C, Maggi RG, Breitschwerdt EB. Neurobartonelloses: emerging from obscurity! Parasites & Vectors. 2024. PMID: 39369199
- Delaney S, et al. Bartonella species bacteremia in association with adult psychosis. Frontiers in Psychiatry. 2024. DOI: 10.3389/fpsyt.2024.1388442
- Breitschwerdt EB, Maggi RG, Moore CO, Robveille C, et al. A one health zoonotic vector borne infectious disease family outbreak investigation. Pathogens. 2025. DOI: 10.3390/pathogens14020110
- Breitschwerdt EB, Bradley JM, Maggi RG, Lashnits E, Reicherter P. Bartonella associated cutaneous lesions (BACL) in people with neuropsychiatric symptoms. Pathogens. 2020. DOI: 10.3390/pathogens9121023
- CDC. Bartonella infection (cat scratch disease): prevention and transmission. cdc.gov/bartonella