.interaction-page{--interaction-paper:#efede8;--interaction-panel:#f7f5f0;--interaction-ink:#171512;--interaction-body:#4c463f;--interaction-muted:#6d665e;--interaction-accent:#f04a2a;--interaction-accent-text:#c33a24;max-width:1160px;color:var(--interaction-ink);margin:0 auto;padding:28px 28px 64px;font-family:Inter,system-ui,sans-serif}.interaction-page :is(h1,h2,h3,h4,p,dl,dd){margin:0}.interaction-page :is(h1,h2,h3,h4,button,input){font-family:inherit}.interaction-page button{cursor:pointer}.interaction-page a{color:inherit;text-underline-offset:4px}.interaction-page :is(button,a,input,summary):focus-visible{outline:3px solid var(--interaction-accent-text);outline-offset:4px}.interaction-page ::selection{background:var(--interaction-ink);color:#fff}.interaction-page [hidden]{display:none!important}.interaction-breadcrumbs{color:var(--interaction-muted);flex-wrap:wrap;align-items:center;gap:10px;font-size:13px;display:flex}.interaction-breadcrumbs a{align-items:center;min-height:44px;display:inline-flex}.interaction-hero{grid-template-columns:1.4fr 1fr;align-items:end;gap:48px;padding:24px 0 32px;display:grid}.interaction-hero h1{letter-spacing:-.04em;text-wrap:balance;font-size:clamp(36px,4.6vw,64px);font-weight:850;line-height:1.04}.interaction-hero h1 span{text-decoration:underline;text-decoration-color:var(--interaction-accent);text-underline-offset:8px;text-decoration-thickness:5px}.interaction-hero p{color:var(--interaction-body);max-width:42ch;font-size:16px;line-height:1.65}.interaction-page .interaction-source-check{max-width:90ch;color:var(--interaction-body);margin:-8px 0 24px;font-size:14px;line-height:1.6}.interaction-source-check a{color:var(--interaction-accent-text);font-weight:600;text-decoration:underline}.interaction-search{background:var(--interaction-panel);border:2px solid var(--interaction-ink);box-shadow:5px 5px 0 var(--interaction-ink);padding:24px 28px 20px}.interaction-search label{margin-bottom:12px;font-size:18px;font-weight:750;display:block}.interaction-search-field{border-bottom:2px solid var(--interaction-ink);background:#fff;align-items:center;display:flex}.interaction-search-field:focus-within{border-color:var(--interaction-accent-text);outline:2px solid var(--interaction-accent-text);outline-offset:3px}.interaction-search input{width:100%;min-width:0;color:var(--interaction-ink);caret-color:var(--interaction-accent-text);background:0 0;border:0;border-radius:0;padding:16px;font-size:clamp(18px,2vw,24px)}.interaction-search input::placeholder{color:var(--interaction-muted);opacity:1}.interaction-search input:focus-visible{outline:none}.interaction-search-field button{min-height:44px;color:var(--interaction-body);text-underline-offset:3px;background:0 0;border:0;flex-shrink:0;margin-right:4px;padding:8px 12px;font-size:13px;text-decoration:underline}.interaction-search p{color:var(--interaction-muted);margin-top:12px;font-size:13px;line-height:1.5}.interaction-categories{border-bottom:1px solid var(--interaction-ink);flex-wrap:wrap;column-gap:28px;margin-top:28px;display:flex}.interaction-categories button{min-height:48px;color:var(--interaction-body);background:0 0;border:0;border-bottom:4px solid #0000;justify-content:center;align-items:center;gap:10px;padding:14px 0;font-size:15px;font-weight:650;display:inline-flex}.interaction-categories button[aria-pressed=true]{border-bottom-color:var(--interaction-accent);color:var(--interaction-ink);font-weight:800}.interaction-categories button span{color:var(--interaction-muted);font-variant-numeric:tabular-nums;font-size:13px}.interaction-filter-line{border-bottom:1px solid color-mix(in srgb, var(--interaction-ink) 22%, transparent);padding:12px 0}.interaction-actions{flex-wrap:wrap;align-items:center;gap:6px;display:flex}.interaction-actions>span{color:var(--interaction-muted);padding-right:10px;font-size:13px}.interaction-actions button{min-height:44px;color:var(--interaction-body);background:0 0;border:1px solid #0000;padding:8px 12px;font-size:12px;font-weight:700}.interaction-actions button[aria-pressed=true]{border-color:var(--interaction-ink);color:var(--interaction-ink);background:#fff}.interaction-key{margin-top:4px}.interaction-key summary{cursor:pointer;width:fit-content;min-height:44px;color:var(--interaction-body);text-underline-offset:4px;align-content:center;font-size:13px;text-decoration:underline}.interaction-key dl{grid-template-columns:repeat(2,minmax(0,1fr));gap:20px 32px;padding:16px 0 24px;display:grid}.interaction-key dt{margin-bottom:6px;font-size:12px;font-weight:800}.interaction-key dd{color:var(--interaction-body);font-size:14px;line-height:1.55}.interaction-result-status{min-height:52px;color:var(--interaction-muted);flex-wrap:wrap;justify-content:space-between;align-items:center;gap:12px;padding-top:12px;font-size:13px;display:flex}.interaction-result-status button,.interaction-notice button{min-height:44px;color:var(--interaction-accent-text);text-underline-offset:4px;background:0 0;border:0;padding:8px 0;font-size:13px;text-decoration:underline}.interaction-results-section{margin-top:24px}.interaction-results-section+.interaction-results-section{margin-top:48px}.interaction-results-section>header{justify-content:space-between;align-items:baseline;gap:20px;display:flex}.interaction-results-section h2{letter-spacing:-.025em;font-size:clamp(24px,2.5vw,32px);font-weight:800;line-height:1.15}.interaction-results-section>header>span{color:var(--interaction-muted);flex-shrink:0;font-size:13px}.interaction-section-description{max-width:72ch;color:var(--interaction-body);font-size:14px;line-height:1.6;margin:8px 0 20px!important}.interaction-rows{border-top:2px solid var(--interaction-ink)}.interaction-row{border-bottom:1px solid color-mix(in srgb, var(--interaction-ink) 35%, transparent);scroll-margin-top:100px}.interaction-row h3{font-weight:inherit}.interaction-row-toggle{text-align:left;width:100%;color:var(--interaction-ink);background:0 0;border:0;grid-template-columns:minmax(0,1fr) 210px 24px;align-items:center;gap:24px;padding:22px 16px;display:grid}.interaction-row-copy strong{letter-spacing:-.02em;font-size:20px;font-weight:750;line-height:1.25;display:block}.interaction-row-copy>span{color:var(--interaction-body);margin-top:6px;font-size:15px;font-weight:400;line-height:1.5;display:block}.interaction-row-meta{flex-direction:column;align-items:flex-start;gap:8px;display:flex}.interaction-action{letter-spacing:.035em;border:1px solid var(--interaction-muted);background:var(--interaction-panel);color:var(--interaction-ink);padding:5px 8px;font-size:11px;font-weight:800;line-height:1.3;display:inline-block}.interaction-action[data-level=AVOID]{border:2px solid var(--interaction-accent-text);color:var(--interaction-accent-text);padding:4px 7px}.interaction-evidence{color:var(--interaction-muted);font-size:12px;font-weight:500;line-height:1.4}.interaction-expander{color:var(--interaction-accent-text);font-size:28px;font-weight:400;line-height:1}.interaction-disclosure[open]{background:var(--interaction-panel)}.interaction-row-toggle{cursor:pointer;list-style:none}.interaction-row-toggle::-webkit-details-marker{display:none}.interaction-expander:before{content:"+"}.interaction-disclosure[open]>summary .interaction-expander:before{content:"−"}.interaction-urgent-advice{border-left:3px solid var(--interaction-accent-text);margin:16px 0;padding:16px;font-size:14px;line-height:1.6}.interaction-urgent-advice p{margin:8px 0}.interaction-expanded{padding:0 28px 28px}.interaction-detail{border-top:1px solid color-mix(in srgb, var(--interaction-ink) 18%, transparent);grid-template-columns:160px minmax(0,1fr);gap:24px;padding:16px 0;display:grid}.interaction-detail dt{color:var(--interaction-body);font-size:14px;font-weight:650}.interaction-detail dd{color:var(--interaction-body);max-width:72ch;font-size:16px;line-height:1.65}.interaction-detail dd strong{color:var(--interaction-ink);font-weight:650}.interaction-sources{border-top:1px solid color-mix(in srgb, var(--interaction-ink) 18%, transparent);padding-top:20px}.interaction-sources h4{font-size:15px;font-weight:750}.interaction-sources ul{gap:12px;margin:10px 0 0;padding:0;list-style:none;display:grid}.interaction-sources li{overflow-wrap:anywhere;font-size:14px;line-height:1.6}.interaction-sources a{color:var(--interaction-accent-text);font-weight:600}.interaction-sources li>span{color:var(--interaction-muted)}.interaction-notice{border:1px solid var(--interaction-ink);background:var(--interaction-panel);margin:24px 0;padding:24px;font-size:16px;line-height:1.6}.interaction-notice p{margin-top:8px}.interaction-pharmacist-list{border-top:2px solid var(--interaction-ink);max-width:78ch;margin-top:40px;padding-top:24px}.interaction-pharmacist-list h2{margin-bottom:16px;font-size:clamp(24px,3vw,32px);font-weight:800;line-height:1.2}.interaction-pharmacist-list p,.interaction-pharmacist-list li{color:var(--interaction-body);font-size:16px;line-height:1.65}.interaction-pharmacist-list ul{margin:12px 0;padding-left:24px;list-style:outside}.interaction-pharmacist-list>a{color:var(--interaction-accent-text);margin-top:12px;font-size:14px;display:inline-block}.interaction-page .evidence-policy{border-top:3px solid var(--interaction-ink);margin-top:64px;padding-top:28px}.interaction-page :is(.evidence-policy,.faq-section) h2{letter-spacing:-.03em;margin-bottom:16px;font-size:clamp(24px,3vw,34px);font-weight:800;line-height:1.15}.interaction-page :is(.evidence-policy,.faq-item) p{color:var(--interaction-body);max-width:75ch;margin-bottom:16px;font-size:16px;line-height:1.65}.interaction-page .evidence-grid{grid-template-columns:1fr 1fr;gap:32px;padding:24px 0;display:grid}.interaction-page .evidence-column h3{font-size:17px;font-weight:750}.interaction-page .evidence-column ul{color:var(--interaction-body);padding-left:20px;font-size:15px;line-height:1.65}.interaction-page :is(.evidence-policy,.faq-item) a{color:var(--interaction-accent-text);font-size:14px;font-weight:600;line-height:1.6}.interaction-page .evidence-policy .review-date{color:var(--interaction-muted);margin-top:20px;font-size:13px}.interaction-page .faq-section{border-top:1px solid var(--interaction-ink);margin-top:48px;padding-top:28px}.interaction-page .faq-item{border-bottom:1px solid color-mix(in srgb, var(--interaction-ink) 22%, transparent);padding:24px 0}.interaction-page .faq-item h3{max-width:65ch;margin-bottom:12px;font-size:19px;font-weight:750;line-height:1.4}.interaction-page .action-links{flex-wrap:wrap;gap:16px;margin-top:32px;display:flex}.interaction-page-button{border:1px solid var(--interaction-ink);background:var(--interaction-panel);min-height:48px;color:var(--interaction-ink);align-items:center;padding:12px 18px;font-size:14px;font-weight:650;text-decoration:none;display:inline-flex}.interaction-page .medical-disclaimer{border-top:1px solid var(--interaction-ink);max-width:80ch;color:var(--interaction-body);margin-top:36px;padding-top:20px;font-size:14px;line-height:1.65}.interaction-page .medical-disclaimer strong{color:var(--interaction-ink);margin-bottom:8px;display:block}.interaction-page .print-footer{display:none}@media (hover:hover){.interaction-row-toggle:hover,.interaction-actions button:hover,.interaction-page-button:hover{background:#fff}.interaction-categories button:hover{color:var(--interaction-accent-text)}}@media (width<=700px){.interaction-page{padding:16px 20px 48px}.interaction-hero{grid-template-columns:1fr;gap:20px;padding:20px 0 28px}.interaction-hero h1{max-width:17ch;font-size:clamp(34px,8.8vw,48px)}.interaction-hero p{max-width:60ch;font-size:15px;line-height:1.55}.interaction-search{box-shadow:3px 3px 0 var(--interaction-ink);padding:18px 16px 14px}.interaction-search label{font-size:16px}.interaction-search input{padding:14px 10px;font-size:17px}.interaction-search-field button{padding:6px;font-size:12px}.interaction-categories{grid-template-columns:1fr 1fr;column-gap:20px;margin-top:24px;display:grid}.interaction-categories button{text-align:left;justify-content:space-between;font-size:13px}.interaction-actions{gap:2px}.interaction-actions>span{width:100%;padding:4px 0}.interaction-actions button{padding:8px;font-size:11px}.interaction-key dl,.interaction-page .evidence-grid{grid-template-columns:1fr;gap:20px}.interaction-row-toggle{grid-template-columns:minmax(0,1fr) 24px;gap:12px;padding:20px 4px}.interaction-row-copy strong{font-size:19px}.interaction-row-copy>span{font-size:15px}.interaction-row-meta{flex-flow:wrap;grid-area:2/1;align-items:center;gap:8px 12px}.interaction-expander{grid-area:1/2}.interaction-expanded{padding:0 16px 24px}.interaction-detail{grid-template-columns:1fr;gap:8px}.interaction-result-status{font-size:12px}}@media print{.interaction-page{max-width:none;padding:0;font-size:10pt}.interaction-page :is(.no-print,.interaction-breadcrumbs,.interaction-categories,.interaction-filter-line,.interaction-search,.interaction-result-status){display:none}.interaction-page .interaction-row{break-inside:avoid}.interaction-disclosure::details-content{content-visibility:visible}.interaction-disclosure>.interaction-expanded{display:block!important}.interaction-page .interaction-expander{display:none}.interaction-page .print-footer{margin-top:24px;display:block}.interaction-page h1{font-size:24pt}.interaction-page a[href^=http]:after{content:" (" attr(href) ")";overflow-wrap:anywhere;font-size:8pt}}